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Selected Publications
I have published more than 130 papers, including 97 papers indexed by SCI and 36 papers (Chinese).
30 H-Index by web of science, 32 H-Index by scopus
https://webofscience.clarivate.cn/wos/author/record/IUM-7758-2023
https://www.scopus.com/authid/detail.uri?authorId=17344349500
https://orcid.org/0000-0001-9638-1466
https://scholar.google.com/citations?user=LpPfsEwAAAAJ&hl=en
https://www.researchgate.net/profile/Zheng-Ruan
2023
65.Quancheng Zhou, Xijun Nan, Shucheng Zhang, Liang Zhang, Jian Chen, Jiayi Li, Honglei Wang, Zheng Ruan*. Effect of 3D Food Printing Processing on Polyphenol System of Loaded Aronia melanocarpa and Post-Processing Evaluation of 3D Printing Products. Foods. 2023, 12(10):2068.
64.Peiheng Han, Yujuan Yu, Li Zhang*, Zheng Ruan. Citrus peel ameliorates mucus barrier damage in HFD-fed mice. J Nutr Biochem. 2023 Feb;112:109206.
https://www.sciencedirect.com/science/article/abs/pii/S0955286322002741?via=ihub
63.Yixin Zou, Wenjiao Ding, You Wu, Tingting Chen, Zheng Ruan*. Puerarin alleviates inflammation and pathological damage in colitis mice by regulating metabolism and gut microbiota. Front Microbiol. 2023 Oct 16;14:1279029.
https://www.frontiersin.org/articles/10.3389/fmicb.2023.1279029/full
2022
62 Zheng Ruan, Yujuan Yu, Peiheng Han, Li Zhang*, Zhongyi Hu. Si-Wu Water Extracts Protect against Colonic Mucus Barrier Damage by Regulating Muc2 Mucin Expression in Mice Fed a High-Fat Diet. Foods. 2022 Aug 18;11(16):2499. Q2-5.2
https://pubmed.ncbi.nlm.nih.gov/36010498/
61 Shiqi Li, Siyan Che, Sunni Chen, Zheng Ruan*, Li Zhang. Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice. Environ Sci Pollut Res Int.2022 Jul 23,
https://pubmed.ncbi.nlm.nih.gov/35871201/
60 Jin Wan, Qiong Yu, Junqiu Luo, Li Zhang, Zheng Ruan*. Effects of ferulic acid on the growth performance, antioxidant capacity, and intestinal development of piglets with intrauterine growth retardation. J Anim Sci, 2022 May 1;100(5):skac144.
https://pubmed.ncbi.nlm.nih.gov/35439319/
59 Rongxue Tang, Haifei Yu, Zheng Ruan*, Li Zhang, Yanwen Xue, Xiaofeng Yuan, Mingge Qi, Yanbin Yao. Effects of food matrix elements (dietary fibres) on grapefruit peel flavanone profile and on faecal microbiota during in vitro fermentation. Food Chemistry. 2022 Mar 1;371:131065.
https://pubmed.ncbi.nlm.nih.gov/34560336/
58 Luqing Song, Tao Wu, Li Zhang, Jin Wan, Zheng Ruan*. Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways. Food Function, 2022 Apr 20;13(8):4562-4575.
https://pubmed.ncbi.nlm.nih.gov/35353100/
57 Tang, R., Yu, H., Qi, M., Yuan, X., Ruan, Z., Hu, C., Xiao, M., Xue, Y., Yao, Y., Liu, Q. Biotransformation of citrus fruits phenolic profiles by mixed probiotics in vitro anaerobic fermentation. LWT-FOOD SCIENCE AND TECHNOLOGY. 2022, 160:113087
http://doi.org/10.1016/j.lwt.2022.113087
56 Sunni Chen, Siyan Che, Shiqi Li, Jin Wan, Zheng Ruan*. High-fat diet exacerbated decabromodiphenyl ether-induced hepatocyte apoptosis via intensifying the transfer of Ca2+ from endoplasmic reticulum to mitochondria. Environmental Pollution,2022, 292, 118297.
https://doi.org/10.1016/j.envpol.2021.118297
55 Zheng Ruan*，Fengjie Sun, Xiaodong Xia, Guodong Zhang. Editorial: Interactions Between Bioactive Food Ingredients and Intestinal Microbiota. Front Microbiol ,2022 Apr 22;13:902962.
https://pubmed.ncbi.nlm.nih.gov/35531291/
54 Jin Wan, Li Zhang, Zheng Ruan. Dietary Supplementation with Epicatechin Improves Intestinal Barrier Integrity in Mice. Foods, 2022, 11(20), 3301; https://doi.org/10.3390/foods11203301 DOI 10.3390/foods11203301
2021
53 Jinwen Yuan, Siyan Che, Zheng Ruan*, Luqing Song, Rongxue Tang, Li Zhang. Regulatory effects of flavonoids luteolin on BDE-209-induced intestinal epithelial barrier damage in Caco-2 cell monolayer model. Food and Chemical Toxicology, 2021,150:112098.
https://doi.org/10.1016/j.fct.2021.112098
52 Jinwen Yuan, Siyan Che, Li Zhang, Zheng Ruan*. Reparative Effects of Ethanol-Induced Intestinal Barrier Injury by Flavonoid Luteolin via MAPK/NF-κB/MLCK and Nrf2 Signaling Pathways. Journal of Agricultural and Food Chemistry, 2021,69(14):4101-4110.
https://pubs.acs.org/doi/full/10.1021/acs.jafc.1c00199
50 Jiaojiao Li, Li Zhang, Tao Wu, Yafei Li, Xiaojun Zhou, Zheng Ruan*. Indole-3-propionic Acid Improved the Intestinal Barrier by Enhancing Epithelial Barrier and Mucus Barrier. Journal of Agricultural and Food Chemistry, 2021, 69(5):1487-1495.
https://doi.org/10.1021/acs.jafc.0c05205
50 Siyan Che, Jinwen Yuan, Sunni Chen, Shiqi Li, Li Zhang, Zheng Ruan*, Yanbin Yao. Hesperidin prevents the combined toxicity of decabromodiphenyl ether and sodium nitrite in vitro. Food and chemical toxicology, 2021, 156, 112410.
https://doi.org/10.1016/j.fct.2021.112410
49 Yilin Liu, Chunyan Xie, Zhenya Zhai, Ze-Yuan Deng, Hugo R De Jonge, Xin Wu*, Zheng Ruan*. Uridine attenuates obesity, ameliorates hepatic lipid accumulation and modifies the gut microbiota composition in mice fed with a high-fat diet. Food & Function 2021, 12 (4), 1829-1840.
https://doi.org/10.1039/D0FO02533J
48 Sunni Chen , Siyan Che , Shiqi Li , Zheng Ruan*. The combined impact of decabromodiphenyl ether and high fat exposure on non-alcoholic fatty liver disease in vivo and in vitro.Toxicology 2021, 464, 153015. Q2-4.5
https://doi.org/10.1016/j.tox.2021.153015
47 Jinwen Yuan, Xiaoming Sun, Siyan Che, Li Zhang, Zheng Ruan*, Xiaomin Li,Junhua Yang. AhR-mediated CYP1A1 and ROS overexpression are involved in hepatotoxicity of decabromodiphenyl ether (BDE-209).Toxicology Letters 2021, 352, 26-33.
https://doi.org/10.1016/j.toxlet.2021.09.008
46 Jinwen Yuan, Siyan Che, Li Zhang, Xiaomin Li, Junhua Yang, Xiaoming Sun*, Zheng Ruan*. Assessing the combinatorial cytotoxicity of the exogenous contamination with BDE-209, bisphenol A, and acrylamide via high-content analysis.Chemosphere 2021, 284, 131346.
https://doi.org/10.1016/j.chemosphere.2021.131346
45 Siyan Che, Sunni Chen, Shiqi Li, Zheng Ruan*. Decabromodiphenyl ether initiates mitochondria-dependent apoptosis by disrupting calcium homeostasis in mice livers. Chemosphere 2021, 132767
https://doi.org/10.1016/j.chemosphere.2021.132767
44 Wu You, Li Jiaojiao, Ding Wenjiao, Ruan, Zheng*, Zhang, Li. Enhanced Intestinal Barriers by Puerarin in Combination with Tryptophan., Journal of Agricultural and Food Chemistry, 2021,69(51): 15575-15584
https://pubs.acs.org/doi/10.1021/acs.jafc.1c05830
43 Yixin Zou, Haifei Yu, Li Zhang, Ruan Zheng*. Dietary Vegetable Powders Modulate Immune Homeostasis and Intestinal Microbiota in Mice. Foods, 2022 Jan; 11(1): 27. https://pubmed.ncbi.nlm.nih.gov/35010153/
42 Meiyi Hu, Li Zhang, Ruan Zheng*, The Regulatory Effects of Citrus Peel Powder on Liver Metabolites and Gut Flora in Mice with Non-Alcoholic Fatty Liver Disease (NAFLD).Foods . 2021 Dec 6;10(12):3022.
https://pubmed.ncbi.nlm.nih.gov/34945573/
2020
41 Jiaojiao Li, Li Zhang*, Yafei Li, Yi Wu, Tao Wu, Hua Feng, Zhenjiang Xu, Yuhuan Liu, Zheng Ruan*, Shicheng Zhou. Puerarin improves intestinal barrier function through enhancing goblet cells and mucus barrier. Journal of Functional Foods, 2020, 75:104246.
https://doi.org/10.1016/j.jff.2020.104246
40 Yi Wu, Yafei Li*, Zheng Ruan*, Jiaojiao Li, Li Zhang, Hui Lu, and Zhenjiang Xu. Puerarin Rebuilding the Mucus Layer and Regulating Mucin-utilizing Bacteria to Relieve Ulcerative Colitis. Journal of Agricultural and Food Chemistry, 2020, 68(41):11402-11411.
https://doi.org/10.1021/acs.jafc.0c04119
39 Si-yan Che, Jin-wen Yuan, Li Zhang*, Zheng Ruan*, Xiao-ming Sun, Hui Lu. Puerarin prevents epithelial tight junction dysfunction induced by ethanol in Caco-2 cell model. Journal of Functional Foods, 2020, 73:104079.
https://doi.org/10.1016/j.jff.2020.104079
38 Gang Yang, Yali Yan, Li Zhang*, Zheng Ruan*, Xiaoqing Hu, Shuo Zhang, Xiaozhen Li. Porcine circovirus type 2 (PCV2) and Campylobacter infection induce diarrhea in piglets:Microbial dysbiosis and intestinal disorder. Animal Nutrition, 2020, 6(03):362-371.
https://doi.org/10.1016/j.aninu.2020.05.003
37 Quancheng Zhou, Meng Wang, Hui Li, Sai Wang, Wanting Sun, Xuanhong Chen, Leichao Dong, Zheng Ruan*. Application of Maillard reaction product of xylose-pea protein enzymatic hydrolysate in 3D printing. Journal of the Science of Food and Agriculture, 2020, 100(7):2982-2990.
http://doi.org/10.1002/jsfa.10327
2019
36 Yanwen Xue, Fang Huang, Rongxue Tang, Qingsheng Fan, Bing Zhang, Zhenjiang Xu, Xiaoming Sun*, Zheng Ruan*. Chlorogenic acid attenuates cadmium-induced intestinal injury in Sprague–Dawley rats. Food and Chemical Toxicology, 2019, 133:110751.
https://doi.org/10.1016/j.fct.2019.110751
35 Zhenlong Chen, Yuhui Yang, Shumei Mi, Qingsheng Fan, Xiaoming Sun, Baichuan Deng, Guoyao Wu, Yafei Li*, Quancheng Zhou, Zheng Ruan*. Hepatoprotective effect of chlorogenic acid against chronic liver injury in inflammatory rats. Journal of Functional Foods, 2019, 62:103540. https://www.sciencedirect.com/science/article/abs/pii/S1756464619304645
http://doi.org/10.1016/j.jff.2019.103540
34 Yilin Liu, Yumei Zhang, Jie Yin, Zheng Ruan*, Xin Wu* & Yulong Yin. Uridine dynamic administration affects circadian variations in lipid metabolisms in the liver of high-fat-diet-fed mice. chronobiology international, 2019, 36:1258-1267.
https://doi.org/10.1080/07420528.2019.1637347
33 Mengdie Chen, Yuyu Liu, Shanbai Xiong, Moucheng Wu, Bin Li, Zheng Ruan*, Xiaobo Hu*. Dietary L-tryptophan alleviated LPS-induced intestinal barrier injury by regulating tight junctions in a Caco-2 cell monolayer model. Food & Function, 2019, 10(5):2390-2398.
https://doi.org/10.1039/c9fo00123a
32 Dan Wan, Qinghua Wu, Hengjia Ni, Gang Liu*, Zheng Ruan*, Yulong Yin. Treatments for Iron Deficiency (ID): Prospective Organic Iron Fortification. Current Pharmaceutical Design, 2019, 25(3):325-332.
https://doi.org/10.2174/1381612825666190319111437
31 Yilin Liu, Dan Wan, Xihong Zhou, Zheng Ruan, Tianyong Zhang, Xin Wu*, Yulong Yin. Effects of dynamic feeding low- and high-methionine diets on the variation of glucose and lipid metabolism-related genes in the liver of laying hens. Poult Sci. 2019, 98(5):2231-2240. https://doi.org/10.3382/ps/pey589
25, Yi Wu, Wenhui Liu, Qi Li, Yafei Li, Yali Yan, Fang Huang, Xin Wu, Quancheng Zhou, Xugang Shu*, Zheng Ruan*. Dietary chlorogenic acid regulates gut microbiota, serum-free amino acids and colonic serotonin levels in growing pigs. International Journal of Food Sciences and Nutrition, 2018, 69(5):566-573.
https://doi.org/10.1080/09637486.2017.1394449
24, Wenhui Liu, Shumei Mi, Zheng Ruan*, Jing Li, Xugang Shu, Kang Yao, Min Jiang, Zeyuan Deng. Dietary Tryptophan Enhanced the Expression of Tight Junction Protein ZO-1 in Intestine. Journal of Food Science, 2017 , 82(2):562-567.
https://doi.org/10.1111/1750-3841.13603
23, Yan Zhoua, Zheng Ruan*, Lili Zhou, Xugang Shu, Xiaohong Sun, Shumei Mi, Yuhui Yang, Yulong Yina *. Chlorogenic acid ameliorates endotoxin-induced liver injury by shifting energy metabolism from glycolysis to mitochondrial biogenesis. Biochemical and Biophysical Research Communications, 2016, Accepted.
22, X.L. Li, M. Jiang, Z. Ruan*, S.M. Mi, X. Wu, K. Yao, X. Xiong, Y. Zhou, Y. L. Yin. Tryptophan increases intestinal permeability and decreases intestinal tight junction protein expression in weanling piglets. Journal of Animal Science, 2016, Accepted.
21, Yan Zhou, Lili Zhou, Zheng Ruan*, Shumei Mi, Min Jiang, Xiaolan Li, Xin Wu, Zeyuan Deng, Yulong Yin. Chlorogenic Acid Ameliorates Intestinal Mitochondrial Injury by Increasing Antioxidant Effects and Activity of Respiratory Complexes. Bioscience, Biotechnology, and Biochemistry, 2016, Accepted.
20, Yan Zhou, Zheng Ruan,* Yanmei Wen, Yuhui Yang, Shumei Mi, Lili Zhou, Xin Wu, Sheng Ding,Zeyuan Deng, Guoyao Wu, Yulong Yin. Chlorogenic acid from honeysuckle improves hepatic lipid dysregulation and modulates hepatic fatty acid composition in rats with chronic endotoxin infusion. Journal of Clinical Biochemistry and Nutrition, 2016, Accepted.
19, Yan Zhou, Zheng Ruan*, Lili Zhou, Yuhui Yang, Shumei Mi, Zeyuan Deng, Yulong Yin. Chlorogenic acid decreased intestinal permeability and ameliorated intestinal injury in rats via amelioration of mitochondrial respiratory chain dysfunction. Food Science and Biotechnology, 2016, Accepted.
18, Yan Zhou, Zheng Ruan*, Xiaoli Zhou, Xiaoliu Huang, Hua Li, Ling Wang, Cui Zhang, Zeyuan Deng, Guoyao Wu, Yulong Yin. Lactosucrose attenuates intestinal inflammation by promoting Th2 cytokine production and enhancing CD86 expression in colitic rats. Bioscience, Biotechnology, and Biochemistry. 2015, 79(4):643–651. http://www.tandfonline.com/doi/full/10.1080/09168451.2014.991680
17, Yan Zhou, Zheng Ruan*, Xiaoli Zhou, Xiaoliu Huang, Hua Li, Ling Wang, Cui Zhang, Shiqiang Liu, Zeyuan Deng, Guoyao Wu, Yulong Yin. Diet with lactosucrose supplementation ameliorates trinitrobenzene sulfonic acid-induced colitis in rats. Food Function, 2015, 6:161-171. http://pubs.rsc.org/en/content/articlepdf/2014/fo/c4fo00381k
16, Zheng Ruan, Yuhui Yang, Yanmei Wen, Yan Zhou, Xiaofang Fu, Sheng Ding, Gang Liu, Kang Yao, Xin Wu, Zeyuan Deng, Guoyao Wu, Yulong Yin*. Metabolomic analysis of amino acid and fat metabolism in rats with L-tryptophan supplementation. Amino Acids. 2014, 46: 2681-2691. http://www.ncbi.nlm.nih.gov/pubmed/25139634
15, Zheng Ruan, Yuhui Yang, Yan Zhou, Yanmei Wen, Sheng Ding, Gang Liu, Xin Wu, Peng Liao*, Zeyuan Deng, Houssein Assaad, Guoyao Wu, Yulong Yin*. Metabolomic analysis of amino acid and energy metabolism in rats supplemented with chronic chlorogenic acid. Amino Acids, 2014, 46: 2219-2229. http://www.ncbi.nlm.nih.gov/pubmed/24927697
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